Since the research showing choline enhances memory in the offspring mammals that received choline supplements during pregnancy first became public in the mid to late 1990s, researchers have wonder about the exact process by which this could be taking place. Why did the memories of these offspring of mothers that received higher choline levels have better memories, and what was the exact chemical or molecular process by which it took place.
A research paper published in March, 2004 has identified what looks to be the exact process by which the memory enhancement occurs. Of specific interest is that this new resarch paper has been done by the original researchers who did the early research that revealed the Choline/memory link. Following is a write up of the paper:
Paper: Prenatal Choline supplementation advances hippocampal development and enhances MAPK and CREB activation (by J. Blusztajn, C Williams, W. Meck, T Mellott).
Principal Findings of this research paper:
1. Prenatal choline supplementation enhances the ability of juvenile rats to use relational cues in a water maze task (demonstrating an advancement in the supplemented group of approximately a 20% improvement in their spacial navigational abilities.
A research paper published in March, 2004 has identified what looks to be the exact process by which the memory enhancement occurs. Of specific interest is that this new resarch paper has been done by the original researchers who did the early research that revealed the Choline/memory link. Following is a write up of the paper:
Paper: Prenatal Choline supplementation advances hippocampal development and enhances MAPK and CREB activation (by J. Blusztajn, C Williams, W. Meck, T Mellott).
Principal Findings of this research paper:
1. Prenatal choline supplementation enhances the ability of juvenile rats to use relational cues in a water maze task (demonstrating an advancement in the supplemented group of approximately a 20% improvement in their spacial navigational abilities.
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